diff --git a/pkgs/development/python-modules/six/default.nix b/pkgs/development/python-modules/six/default.nix
index 775dd4b3992e..afaedae9529e 100644
--- a/pkgs/development/python-modules/six/default.nix
+++ b/pkgs/development/python-modules/six/default.nix
@@ -1,6 +1,7 @@
 { lib
 , buildPythonPackage
 , fetchPypi
+, isPyPy
 , pytestCheckHook
 }:
 
@@ -19,6 +20,11 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
+  pytestFlagsArray = if isPyPy then [
+    # uses ctypes to find native library
+    "--deselect=test_six.py::test_move_items"
+  ] else null;
+
   pythonImportsCheck = [ "six" ];
 
   meta = {