diff --git a/pkgs/development/python-modules/pyquil/default.nix b/pkgs/development/python-modules/pyquil/default.nix
new file mode 100644
index 000000000000..c9f71b6414db
--- /dev/null
+++ b/pkgs/development/python-modules/pyquil/default.nix
@@ -0,0 +1,93 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, importlib-metadata
+, ipython
+, lark-parser
+, networkx
+, numpy
+, poetry-core
+, pytest-asyncio
+, pytest-freezegun
+, pytest-httpx
+, pytest-mock
+, pytestCheckHook
+, pythonOlder
+, qcs-api-client
+, retry
+, rpcq
+, scipy
+}:
+
+buildPythonPackage rec {
+  pname = "pyquil";
+  version = "3.0.0";
+  format = "pyproject";
+
+  disabled = pythonOlder "3.7";
+
+  src = fetchFromGitHub {
+    owner = "rigetti";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "0070pslz6vvyavm5pm27q2bng2mfmkb41v5czzckz7m8db3b1r2x";
+  };
+
+  nativeBuildInputs = [
+    poetry-core
+  ];
+
+  propagatedBuildInputs = [
+    lark-parser
+    networkx
+    numpy
+    qcs-api-client
+    retry
+    rpcq
+    scipy
+  ] ++ lib.optionals (pythonOlder "3.8") [
+    importlib-metadata
+  ];
+
+  checkInputs = [
+    pytest-asyncio
+    pytest-freezegun
+    pytest-httpx
+    pytest-mock
+    pytestCheckHook
+    ipython
+  ];
+
+  postPatch = ''
+    substituteInPlace pyproject.toml \
+      --replace 'lark = "^0.11.1"' 'lark-parser = ">=0.11.1"'
+  '';
+
+  disabledTestPaths = [
+    # Tests require network access
+    "test/e2e/"
+    "test/unit/test_api.py"
+    "test/unit/test_operator_estimation.py"
+    "test/unit/test_wavefunction_simulator.py"
+    "test/unit/test_compatibility_v2_operator_estimation.py"
+    "test/unit/test_compatibility_v2_quantum_computer.py"
+    "test/unit/test_compatibility_v2_qvm.py"
+    "test/unit/test_quantum_computer.py"
+    "test/unit/test_qvm.py"
+    "test/unit/test_reference_wavefunction.py"
+  ];
+
+  disabledTests = [
+    "test_compile_with_quilt_calibrations"
+    "test_sets_timeout_on_requests"
+  ];
+
+  pythonImportsCheck = [ "pyquil" ];
+
+  meta = with lib; {
+    description = "Python library for creating Quantum Instruction Language (Quil) programs";
+    homepage = "https://github.com/rigetti/pyquil";
+    license = licenses.asl20;
+    maintainers = with maintainers; [ fab ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 5494755526f1..90681a6f374e 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -1465,8 +1465,6 @@ in {
 
   cirq-google = callPackage ../development/python-modules/cirq-google { };
 
-  cirq-rigetti = callPackage ../development/python-modules/cirq-rigetti { };
-
   cirq-pasqal = callPackage ../development/python-modules/cirq-pasqal { };
 
   cirq-web = callPackage ../development/python-modules/cirq-web { };
@@ -6655,6 +6653,8 @@ in {
 
   pyquery = callPackage ../development/python-modules/pyquery { };
 
+  pyquil = callPackage ../development/python-modules/pyquil { };
+
   pyrabbit2 = callPackage ../development/python-modules/pyrabbit2 { };
 
   pyrad = callPackage ../development/python-modules/pyrad { };