diff --git a/pkgs/development/python-modules/siuba/default.nix b/pkgs/development/python-modules/siuba/default.nix
new file mode 100644
index 000000000000..97d90cac25ae
--- /dev/null
+++ b/pkgs/development/python-modules/siuba/default.nix
@@ -0,0 +1,62 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, pythonOlder
+, pytestCheckHook
+, hypothesis
+, numpy
+, pandas
+, psycopg2
+, pymysql
+, python-dateutil
+, pytz
+, pyyaml
+, six
+, sqlalchemy
+}:
+
+buildPythonPackage rec {
+  pname = "siuba";
+  version = "0.4.2";
+  disabled = pythonOlder "3.7";
+
+  format = "setuptools";
+
+  src = fetchFromGitHub {
+    owner = "machow";
+    repo = "siuba";
+    rev = "refs/tags/v${version}";
+    hash = "sha256-Q2nkK51bmIO2OcBuWu+u7yB8UmaqiZJXpuxXcytTlUY=";
+  };
+
+  propagatedBuildInputs = [
+    numpy
+    pandas
+    psycopg2
+    pymysql
+    python-dateutil
+    pytz
+    pyyaml
+    six
+    sqlalchemy
+  ];
+
+  checkInputs = [
+    hypothesis
+    pytestCheckHook
+  ];
+  doCheck = false;
+  # requires running mysql and postgres instances; see docker-compose.yml
+
+  pythonImportsCheck = [
+    "siuba"
+    "siuba.data"
+  ];
+
+  meta = with lib; {
+    description = "Use dplyr-like syntax with pandas and SQL";
+    homepage = "https://siuba.org";
+    license = licenses.mit;
+    maintainers = with maintainers; [ bcdarwin ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 8ce5080662a8..43a5fd410bd1 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -10507,6 +10507,8 @@ self: super: with self; {
 
   sip_4 = callPackage ../development/python-modules/sip/4.x.nix { };
 
+  siuba = callPackage ../development/python-modules/siuba { };
+
   six = callPackage ../development/python-modules/six { };
 
   sjcl = callPackage ../development/python-modules/sjcl { };