diff --git a/pkgs/development/tools/wasmedge/default.nix b/pkgs/development/tools/wasmedge/default.nix
index 6f5d9162c5b7..edcdf0d8c1e1 100644
--- a/pkgs/development/tools/wasmedge/default.nix
+++ b/pkgs/development/tools/wasmedge/default.nix
@@ -5,6 +5,9 @@
 , cmake
 , gtest
 , spdlog
+, Foundation
+, libxml2
+, libffi
 }:
 
 llvmPackages.stdenv.mkDerivation rec {
@@ -18,6 +21,11 @@ llvmPackages.stdenv.mkDerivation rec {
     sha256 = "sha256-P2Y2WK6G8aEK1Q4hjrS9X+2WbOfy4brclB/+SWP5LTM=";
   };
 
+  nativeBuildInputs = [
+    cmake
+    llvmPackages.lld
+  ] ++ lib.optionals llvmPackages.stdenv.isDarwin [ Foundation ];
+
   buildInputs = [
     boost
     spdlog
@@ -31,7 +39,7 @@ llvmPackages.stdenv.mkDerivation rec {
   cmakeFlags = [
     "-DCMAKE_BUILD_TYPE=Release"
     "-DWASMEDGE_BUILD_TESTS=OFF" # Tests are downloaded using git
-  ];
+  ] ++ lib.optional llvmPackages.stdenv.isDarwin "-DWASMEDGE_FORCE_DISABLE_LTO=ON";
 
   meta = with lib; {
     homepage = "https://wasmedge.org/";
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index a2c26c8dddda..70a72b0395d2 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -13074,6 +13074,7 @@ with pkgs;
 
   wasmedge = callPackage ../development/tools/wasmedge {
     llvmPackages = llvmPackages_12;
+    inherit (darwin.apple_sdk.frameworks) Foundation;
   };
 
   welkin = callPackage ../tools/graphics/welkin {};