diff --git a/pkgs/applications/audio/samplebrain/default.nix b/pkgs/applications/audio/samplebrain/default.nix
new file mode 100644
index 000000000000..942e7bccc13c
--- /dev/null
+++ b/pkgs/applications/audio/samplebrain/default.nix
@@ -0,0 +1,62 @@
+{ lib
+, stdenv
+, fetchFromGitLab
+, fftw
+, liblo
+, libsndfile
+, makeDesktopItem
+, portaudio
+, qmake
+, qtbase
+, wrapQtAppsHook
+}:
+
+stdenv.mkDerivation rec {
+  pname = "samplebrain";
+  version = "0.18.5";
+
+  src = fetchFromGitLab {
+    owner = "then-try-this";
+    repo = "samplebrain";
+    rev = "v${version}_release";
+    hash = "sha256-/pMHmwly5Dar7w/ZawvR3cWQHw385GQv/Wsl1E2w5p4=";
+  };
+
+  nativeBuildInputs = [
+    qmake
+    wrapQtAppsHook
+  ];
+
+  buildInputs = [
+    fftw
+    liblo
+    libsndfile
+    portaudio
+    qtbase
+  ];
+
+  desktopItem = makeDesktopItem {
+    type = "Application";
+    desktopName = pname;
+    name = pname;
+    comment = "A sample masher designed by Aphex Twin";
+    exec = pname;
+    icon = pname;
+    categories = [ "Audio" ];
+  };
+
+  installPhase = ''
+    mkdir -p $out/bin
+    cp samplebrain $out/bin
+    install -m 444 -D desktop/samplebrain.svg $out/share/icons/hicolor/scalable/apps/samplebrain.svg
+  '';
+
+  meta = with lib; {
+    description = "A custom sample mashing app";
+    homepage = "https://thentrythis.org/projects/samplebrain";
+    changelog = "https://gitlab.com/then-try-this/samplebrain/-/releases/v${version}_release";
+    maintainers = with maintainers; [ mitchmindtree ];
+    license = licenses.gpl2;
+    platforms = platforms.linux;
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 979735e37135..c543c0a07d71 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -15579,6 +15579,8 @@ with pkgs;
 
   mruby = callPackage ../development/compilers/mruby { };
 
+  samplebrain = libsForQt5.callPackage ../applications/audio/samplebrain { };
+
   scsh = callPackage ../development/interpreters/scsh { };
 
   scheme48 = callPackage ../development/interpreters/scheme48 { };