diff --git a/pkgs/applications/networking/browsers/firefox/122.0-libvpx-mozbz1875201.patch b/pkgs/applications/networking/browsers/firefox/122.0-libvpx-mozbz1875201.patch
deleted file mode 100644
index 4acf0fa6a7fc..000000000000
--- a/pkgs/applications/networking/browsers/firefox/122.0-libvpx-mozbz1875201.patch
+++ /dev/null
@@ -1,80 +0,0 @@
-This patch is a rebase of https://bugzilla.mozilla.org/attachment.cgi?id=9377318
-on top of Firefox 122.0.
-
-Fixes: https://bugzilla.mozilla.org/show_bug.cgi?id=1875201
-
-diff --git a/third_party/libwebrtc/modules/video_coding/webrtc_libvpx_interface_gn/moz.build b/third_party/libwebrtc/modules/video_coding/webrtc_libvpx_interface_gn/moz.build
-index c5dabce8b0..e325905282 100644
---- a/third_party/libwebrtc/modules/video_coding/webrtc_libvpx_interface_gn/moz.build
-+++ b/third_party/libwebrtc/modules/video_coding/webrtc_libvpx_interface_gn/moz.build
-@@ -5,6 +5,8 @@
- 
-   ### This moz.build was AUTOMATICALLY GENERATED from a GN config,  ###
-   ### DO NOT edit it by hand.                                       ###
-+if not CONFIG["MOZ_SYSTEM_LIBVPX"]:
-+    LOCAL_INCLUDES += [ "/media/libvpx/libvpx/" ]
- 
- COMPILE_FLAGS["OS_INCLUDES"] = []
- AllowCompilerWarnings()
-@@ -25,7 +27,6 @@ LOCAL_INCLUDES += [
-     "!/ipc/ipdl/_ipdlheaders",
-     "!/third_party/libwebrtc/gen",
-     "/ipc/chromium/src",
--    "/media/libvpx/libvpx/",
-     "/third_party/libwebrtc/",
-     "/third_party/libwebrtc/third_party/abseil-cpp/",
-     "/tools/profiler/public"
-diff --git a/third_party/libwebrtc/modules/video_coding/webrtc_vp8_gn/moz.build b/third_party/libwebrtc/modules/video_coding/webrtc_vp8_gn/moz.build
-index 77a6b3870b..d515bc0595 100644
---- a/third_party/libwebrtc/modules/video_coding/webrtc_vp8_gn/moz.build
-+++ b/third_party/libwebrtc/modules/video_coding/webrtc_vp8_gn/moz.build
-@@ -5,6 +5,8 @@
- 
-   ### This moz.build was AUTOMATICALLY GENERATED from a GN config,  ###
-   ### DO NOT edit it by hand.                                       ###
-+if not CONFIG["MOZ_SYSTEM_LIBVPX"]:
-+    LOCAL_INCLUDES += [ "/media/libvpx/libvpx/" ]
- 
- COMPILE_FLAGS["OS_INCLUDES"] = []
- AllowCompilerWarnings()
-@@ -25,7 +27,6 @@ LOCAL_INCLUDES += [
-     "!/ipc/ipdl/_ipdlheaders",
-     "!/third_party/libwebrtc/gen",
-     "/ipc/chromium/src",
--    "/media/libvpx/libvpx/",
-     "/media/libyuv/",
-     "/media/libyuv/libyuv/include/",
-     "/third_party/libwebrtc/",
-diff --git a/third_party/libwebrtc/modules/video_coding/webrtc_vp9_gn/moz.build b/third_party/libwebrtc/modules/video_coding/webrtc_vp9_gn/moz.build
-index 4bece72807..5cc8d30e1a 100644
---- a/third_party/libwebrtc/modules/video_coding/webrtc_vp9_gn/moz.build
-+++ b/third_party/libwebrtc/modules/video_coding/webrtc_vp9_gn/moz.build
-@@ -5,6 +5,8 @@
- 
-   ### This moz.build was AUTOMATICALLY GENERATED from a GN config,  ###
-   ### DO NOT edit it by hand.                                       ###
-+if not CONFIG["MOZ_SYSTEM_LIBVPX"]:
-+    LOCAL_INCLUDES += [ "/media/libvpx/libvpx/" ]
- 
- COMPILE_FLAGS["OS_INCLUDES"] = []
- AllowCompilerWarnings()
-@@ -25,7 +27,6 @@ LOCAL_INCLUDES += [
-     "!/ipc/ipdl/_ipdlheaders",
-     "!/third_party/libwebrtc/gen",
-     "/ipc/chromium/src",
--    "/media/libvpx/libvpx/",
-     "/media/libyuv/",
-     "/media/libyuv/libyuv/include/",
-     "/third_party/libwebrtc/",
-diff --git a/third_party/libwebrtc/moz.build b/third_party/libwebrtc/moz.build
-index 7baea55b7e..86d4f0f288 100644
---- a/third_party/libwebrtc/moz.build
-+++ b/third_party/libwebrtc/moz.build
-@@ -436,7 +436,6 @@ DIRS += [
-     "/third_party/libwebrtc/third_party/abseil-cpp/absl/types/span_gn",
-     "/third_party/libwebrtc/third_party/abseil-cpp/absl/types/variant_gn",
-     "/third_party/libwebrtc/third_party/abseil-cpp/absl/utility/utility_gn",
--    "/third_party/libwebrtc/third_party/libvpx/libvpx_gn",
-     "/third_party/libwebrtc/third_party/libyuv/libyuv_gn",
-     "/third_party/libwebrtc/third_party/pffft/pffft_gn",
-     "/third_party/libwebrtc/third_party/rnnoise/rnn_vad_gn",
diff --git a/pkgs/applications/networking/browsers/firefox/common.nix b/pkgs/applications/networking/browsers/firefox/common.nix
index 4d28004a0d0d..438f0c3078d5 100644
--- a/pkgs/applications/networking/browsers/firefox/common.nix
+++ b/pkgs/applications/networking/browsers/firefox/common.nix
@@ -234,32 +234,10 @@ buildStdenv.mkDerivation {
     "profilingPhase"
   ];
 
-  patches = lib.optionals (lib.versionAtLeast version "120" && lib.versionOlder version "122") [
-    # dbus cflags regression fix
-    # https://bugzilla.mozilla.org/show_bug.cgi?id=1864083
-    (fetchpatch {
-      url = "https://hg.mozilla.org/mozilla-central/raw-rev/f1f5f98290b3";
-      hash = "sha256-5PzVNJvPNX8irCqj1H38SFDydNJZuBHx167e1TQehaI=";
-    })
-  ]
-  ++ lib.optional (lib.versionAtLeast version "111") ./env_var_for_system_dir-ff111.patch
-  ++ lib.optional (lib.versionAtLeast version "96" && lib.versionOlder version "121") ./no-buildconfig-ffx96.patch
-  ++ lib.optional (lib.versionAtLeast version "121") ./no-buildconfig-ffx121.patch
-  ++ lib.optionals (lib.versionAtLeast version "120" && lib.versionOlder version "120.0.1") [
-    (fetchpatch {
-      # Do not crash on systems without an expected statically assumed page size.
-      # https://phabricator.services.mozilla.com/D194458
-      name = "mozbz1866025.patch";
-      url = "https://hg.mozilla.org/mozilla-central/raw-rev/42c80086da4468f407648f2f57a7222aab2e9951";
-      hash = "sha256-cWOyvjIPUU1tavPRqg61xJ53XE4EJTdsFzadfVxyTyM=";
-    })
-  ]
-  ++ lib.optionals (lib.versionOlder version "122") [
-    ./bindgen-0.64-clang-18.patch
-  ]
-  ++ lib.optionals (lib.versionAtLeast version "122" && lib.versionOlder version "123") [
-    ./122.0-libvpx-mozbz1875201.patch
-  ]
+  patches = lib.optionals (lib.versionAtLeast version "111") [ ./env_var_for_system_dir-ff111.patch ]
+  ++ lib.optionals (lib.versionAtLeast version "96" && lib.versionOlder version "121") [ ./no-buildconfig-ffx96.patch ]
+  ++ lib.optionals (lib.versionAtLeast version "121") [ ./no-buildconfig-ffx121.patch ]
+  ++ lib.optionals (lib.versionOlder version "122") [ ./bindgen-0.64-clang-18.patch  ]
   ++ lib.optionals (lib.versionOlder version "123") [
     (fetchpatch {
       name = "clang-18.patch";
@@ -267,9 +245,6 @@ buildStdenv.mkDerivation {
       hash = "sha256-2IpdSyye3VT4VB95WurnyRFtdN1lfVtYpgEiUVhfNjw=";
     })
   ]
-  ++ lib.optionals (lib.versionOlder version "115.12") [
-    ./rust-1.78.patch
-  ]
   ++ extraPatches;
 
   postPatch = ''