diff --git a/pkgs/development/python-modules/numba/default.nix b/pkgs/development/python-modules/numba/default.nix
index 5eddde4b1af4..f452b7fae738 100644
--- a/pkgs/development/python-modules/numba/default.nix
+++ b/pkgs/development/python-modules/numba/default.nix
@@ -13,12 +13,12 @@
 }:
 
 buildPythonPackage rec {
-  version = "0.45.1";
+  version = "0.46.0";
   pname = "numba";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "41376e8635fa43743ca7ff9b4fb503c0c3315a9243d523b5870207d6199bdfd9";
+    sha256 = "c2cbaeae60f80805290fff50175028726fae12692404a36babd3326730fbceee";
   };
 
   NIX_CFLAGS_COMPILE = stdenv.lib.optionalString stdenv.isDarwin "-I${libcxx}/include/c++/v1";