diff --git a/pkgs/development/python-modules/pyinstrument/default.nix b/pkgs/development/python-modules/pyinstrument/default.nix
index 4cc60efbc637..9848af44925d 100644
--- a/pkgs/development/python-modules/pyinstrument/default.nix
+++ b/pkgs/development/python-modules/pyinstrument/default.nix
@@ -9,7 +9,7 @@
 
 buildPythonPackage rec {
   pname = "pyinstrument";
-  version = "4.5.2";
+  version = "4.5.3";
   format = "pyproject";
 
   disabled = pythonOlder "3.7";
@@ -18,7 +18,7 @@ buildPythonPackage rec {
     owner = "joerick";
     repo = pname;
     rev = "refs/tags/v${version}";
-    hash = "sha256-VL/JzgMxn5zABfmol+5oofR1RjyxTdzvUi6JnwsSFao=";
+    hash = "sha256-rGjHVbIl0kXgscKNZ/U1AU3Ij9Y+iOpIXnmO4jeb3jI=";
   };
 
   nativeBuildInputs = [