diff --git a/pkgs/development/python-modules/nanobind/default.nix b/pkgs/development/python-modules/nanobind/default.nix
index 76f2e9a58d76..3d2005a1c6aa 100644
--- a/pkgs/development/python-modules/nanobind/default.nix
+++ b/pkgs/development/python-modules/nanobind/default.nix
@@ -27,14 +27,14 @@
 }:
 buildPythonPackage rec {
   pname = "nanobind";
-  version = "2.1.0";
+  version = "2.2.0";
   pyproject = true;
 
   src = fetchFromGitHub {
     owner = "wjakob";
     repo = "nanobind";
     rev = "refs/tags/v${version}";
-    hash = "sha256-AO/EHx2TlXidalhPb+xuUchaek4ki7fDExu2foBgUp0=";
+    hash = "sha256-HtZfpMVz/7VMVrFg48IkitK6P3tA+swOeaLLiKguXXk=";
     fetchSubmodules = true;
   };
 
@@ -59,6 +59,13 @@ buildPythonPackage rec {
   dontUseCmakeBuildDir = true;
 
   preCheck = ''
+    # TODO: added 2.2.0, re-enable on next bump
+    # https://github.com/wjakob/nanobind/issues/754
+    # "generated stubs do not match their references"
+    # > -import tensorflow.python.framework.ops
+    # > +import tensorflow
+    rm tests/test_ndarray_ext.pyi.ref
+
     # build tests
     make -j $NIX_BUILD_CORES
   '';