diff --git a/pkgs/development/libraries/qt-6/modules/qtwebengine.nix b/pkgs/development/libraries/qt-6/modules/qtwebengine.nix
index 3741b7c6b6f0..fadbc5d2bfa3 100644
--- a/pkgs/development/libraries/qt-6/modules/qtwebengine.nix
+++ b/pkgs/development/libraries/qt-6/modules/qtwebengine.nix
@@ -127,10 +127,14 @@ qtModule {
   # which cannot be set at the same time as -Wformat-security
   hardeningDisable = [ "format" ];
 
-  # removes macOS 12+ dependencies
   patches = [
+    # removes macOS 12+ dependencies
     ../patches/qtwebengine-darwin-no-low-latency-flag.patch
     ../patches/qtwebengine-darwin-no-copy-certificate-chain.patch
+    # Don't assume /usr/share/X11, and also respect the XKB_CONFIG_ROOT
+    # environment variable, since NixOS relies on it working.
+    # See https://github.com/NixOS/nixpkgs/issues/226484 for more context.
+    ../patches/qtwebengine-xkb-includes.patch
   ];
 
   postPatch = ''
@@ -161,9 +165,6 @@ qtModule {
 
     sed -i -e '/libpci_loader.*Load/s!"\(libpci\.so\)!"${pciutils}/lib/\1!' \
       src/3rdparty/chromium/gpu/config/gpu_info_collector_linux.cc
-
-    substituteInPlace src/3rdparty/chromium/ui/events/ozone/layout/xkb/xkb_keyboard_layout_engine.cc \
-      --replace "/usr/share/X11/xkb" "${xkeyboard_config}/share/X11/xkb"
   ''
   + lib.optionalString stdenv.isDarwin ''
     substituteInPlace configure.cmake \
diff --git a/pkgs/development/libraries/qt-6/patches/qtwebengine-xkb-includes.patch b/pkgs/development/libraries/qt-6/patches/qtwebengine-xkb-includes.patch
new file mode 100644
index 000000000000..5056550ccecd
--- /dev/null
+++ b/pkgs/development/libraries/qt-6/patches/qtwebengine-xkb-includes.patch
@@ -0,0 +1,12 @@
+--- a/src/3rdparty/chromium/ui/events/ozone/layout/xkb/xkb_keyboard_layout_engine.cc	2023-04-19 21:58:29.127258300 +0900
++++ b/src/3rdparty/chromium/ui/events/ozone/layout/xkb/xkb_keyboard_layout_engine.cc	2023-04-19 22:01:35.860196284 +0900
+@@ -637,8 +637,7 @@
+                           .variant = layout_variant.c_str(),
+                           .options = ""};
+   std::unique_ptr<xkb_context, XkbContextDeleter> context;
+-  context.reset(xkb_context_new(XKB_CONTEXT_NO_DEFAULT_INCLUDES));
+-  xkb_context_include_path_append(context.get(), "/usr/share/X11/xkb");
++  context.reset(xkb_context_new(XKB_CONTEXT_NO_FLAGS));
+   std::unique_ptr<xkb_keymap, XkbKeymapDeleter> keymap;
+   keymap.reset(xkb_keymap_new_from_names(context.get(), &names,
+                                          XKB_KEYMAP_COMPILE_NO_FLAGS));