diff --git a/.github/labeler.yml b/.github/labeler.yml
index 074116f1d398..77ed9da6df72 100644
--- a/.github/labeler.yml
+++ b/.github/labeler.yml
@@ -8,6 +8,12 @@
         - pkgs/development/libraries/agda/**/*
         - pkgs/top-level/agda-packages.nix
 
+"6.topic: bsd":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/os-specific/bsd/**/*
+
 "6.topic: cinnamon":
   - any:
     - changed-files:
@@ -21,6 +27,55 @@
         - pkgs/by-name/ne/nemo/**/*
         - pkgs/by-name/ne/nemo-*/**/*
 
+"6.topic: continuous integration":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - .github/**/*
+        - ci/**/*
+
+"6.topic: coq":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/applications/science/logic/coq/**/*
+        - pkgs/development/coq-modules/**/*
+        - pkgs/top-level/coq-packages.nix
+
+"6.topic: crystal":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/development/compilers/crystal/**/*
+
+"6.topic: cuda":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/development/cuda-modules/**/*
+        - pkgs/top-level/cuda-packages.nix
+
+"6.topic: darwin":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/os-specific/darwin/**/*
+        - pkgs/top-level/darwin-aliases.nix
+        - pkgs/top-level/darwin-packages.nix
+
+"6.topic: deepin":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - nixos/modules/services/desktops/deepin/**/*
+        - pkgs/desktops/deepin/**/*
+
+"6.topic: docker tools":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/applications/virtualization/docker/**/*
+
 "6.topic: dotnet":
   - any:
     - changed-files:
@@ -86,6 +141,12 @@
         - pkgs/build-support/flutter/*.nix
         - pkgs/development/compilers/flutter/**/*.nix
 
+"6.topic: games":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/games/**/*
+
 "6.topic: GNOME":
   - any:
     - changed-files:
@@ -105,6 +166,12 @@
         - pkgs/build-support/go/**/*
         - pkgs/development/compilers/go/**/*
 
+"6.topic: hardware":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - nixos/modules/hardware/**/*
+
 "6.topic: haskell":
   - any:
     - changed-files:
@@ -118,6 +185,28 @@
         - pkgs/top-level/haskell-packages.nix
         - pkgs/top-level/release-haskell.nix
 
+"6.topic: java":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - nixos/modules/programs/java.nix
+        - pkgs/development/compilers/graalvm/**/*
+        - pkgs/development/compilers/openjdk/**/*
+        - pkgs/development/compilers/temurin-bin/**/*
+        - pkgs/development/compilers/zulu/**/*
+        - pkgs/development/java-modules/**/*
+        - pkgs/top-level/java-packages.nix
+
+"6.topic: jitsi":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - nixos/modules/services/networking/jitsi-videobridge.nix
+        - nixos/modules/services/web-apps/jitsi-meet.nix
+        - pkgs/servers/web-apps/jitsi-meet/**/*
+        - pkgs/servers/jitsi-videobridge/**/*
+        - pkgs/applications/networking/instant-messengers/jitsi/**/*
+
 "6.topic: julia":
   - any:
     - changed-files:
@@ -205,6 +294,12 @@
         - lib/tests/modules.sh
         - lib/tests/modules/**
 
+"6.topic: musl":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/os-specific/linux/musl/**/*
+
 "6.topic: nixos":
   - any:
     - changed-files:
@@ -213,6 +308,13 @@
         - pkgs/by-name/sw/switch-to-configuration-ng/**/*
         - pkgs/os-specific/linux/nixos-rebuild/**/*
 
+"6.topic: nixos-container":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - nixos/modules/virtualisation/nixos-containers.nix
+        - pkgs/tools/virtualization/nixos-container/**/*
+
 "6.topic: nim":
   - any:
     - changed-files:
@@ -234,6 +336,15 @@
         - pkgs/development/tools/pnpm/**/*
         - pkgs/development/web/nodejs/*
 
+"6.topic: nvidia":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - nixos/modules/hardware/video/nvidia.nix
+        - nixos/modules/services/hardware/nvidia-container-toolkit/**/*
+        - nixos/modules/services/hardware/nvidia-optimus.nix
+        - pkgs/os-specific/linux/nvidia-x11/**/*
+
 "6.topic: ocaml":
   - any:
     - changed-files:
@@ -306,6 +417,19 @@
         - pkgs/development/libraries/kde-frameworks/**/*
         - pkgs/development/libraries/qt-5/**/*
 
+"6.topic: R":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/applications/science/math/R/**/*
+        - pkgs/development/r-modules/**/*
+
+"6.topic: rocm":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/development/rocm-modules/**/*
+
 "6.topic: ruby":
   - any:
     - changed-files:
@@ -374,6 +498,12 @@
         - nixos/tests/make-test-python.nix  # legacy
         # lib/debug.nix has a test framework (runTests) but it's not the main focus
 
+"6.topic: updaters":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/common-updater/**/*
+
 "6.topic: vim":
   - any:
     - changed-files:
@@ -390,6 +520,12 @@
       - any-glob-to-any-file:
         - pkgs/applications/editors/vscode/**/*
 
+"6.topic: windows":
+  - any:
+    - changed-files:
+      - any-glob-to-any-file:
+        - pkgs/os-specific/windows/**/*
+
 "6.topic: xen-project":
   - any:
     - changed-files: