diff --git a/pkgs/development/python-modules/python-arango/default.nix b/pkgs/development/python-modules/python-arango/default.nix
new file mode 100644
index 000000000000..ba44e94b9a31
--- /dev/null
+++ b/pkgs/development/python-modules/python-arango/default.nix
@@ -0,0 +1,138 @@
+{ lib
+, arangodb
+, buildPythonPackage
+, fetchFromGitHub
+, pythonOlder
+, pytestCheckHook
+, pyjwt
+, pytest
+, mock
+, requests
+, requests-toolbelt
+}:
+
+let
+  testDBOpts = {
+    host = "127.0.0.1";
+    port = "8529";
+    password = "test";
+    secret = "secret";
+  };
+in
+
+buildPythonPackage rec {
+  pname = "python-arango";
+  version = "7.5.3";
+  disabled = pythonOlder "3.7";
+  format = "setuptools";
+
+  src = fetchFromGitHub {
+    owner = "ArangoDB-Community";
+    repo = "python-arango";
+    rev = version;
+    sha256 = "0qb2yp05z8dmgsyyxqrl3q0a60jaiih96zhxmqrn2yf7as45n07j";
+  };
+
+  propagatedBuildInputs = [
+    requests
+    requests-toolbelt
+    pyjwt
+  ];
+
+  checkInputs = [
+    arangodb
+    mock
+    pytestCheckHook
+  ];
+
+  # arangodb is compiled only for particular target architectures
+  # (i.e. "haswell"). Thus, these tests may not pass reproducibly,
+  # failing with: `166: Illegal instruction` if not run on arangodb's
+  # specified architecture.
+  #
+  # nonetheless, the client library should remain in nixpkgs - since
+  # the client library will talk to arangodb across the network and
+  # architecture issues will be irrelevant.
+  doCheck = false;
+
+  preCheck = lib.optionalString doCheck ''
+    # Start test DB
+    mkdir -p .nix-test/{data,work}
+
+    ICU_DATA=${arangodb}/share/arangodb3 \
+    GLIBCXX_FORCE_NEW=1 \
+    TZ=UTC \
+    TZ_DATA=${arangodb}/share/arangodb3/tzdata \
+    ARANGO_ROOT_PASSWORD=${testDBOpts.password} \
+    ${arangodb}/bin/arangod \
+      --server.uid=$(id -u) \
+      --server.gid=$(id -g) \
+      --server.authentication=true \
+      --server.endpoint=http+tcp://${testDBOpts.host}:${testDBOpts.port} \
+      --server.descriptors-minimum=4096 \
+      --server.jwt-secret=${testDBOpts.secret} \
+      --javascript.app-path=.nix-test/app \
+      --log.file=.nix-test/log \
+      --database.directory=.nix-test/data \
+      --foxx.api=false &
+  '';
+
+  pytestFlagsArray = [
+    "--host"
+    testDBOpts.host
+    "--port"
+    testDBOpts.port
+    "--passwd"
+    testDBOpts.password
+    "--secret"
+    testDBOpts.secret
+  ];
+
+  disabledTests = [
+    # AssertionError geo-related - try enabling later
+    "test_document_find_in_box"
+
+    # maybe arangod misconfig - try enabling later
+    # arango.exceptions.JWTAuthError: [HTTP 401][ERR 401] Wrong credentials
+    "test_auth_jwt"
+
+    # ValueError - try enabling later
+    # maybe missed 3.9.3->3.10.0 changes
+    # most caused by key change: isNewlyCreated->new
+    "test_add_hash_index"
+    "test_add_skiplist_index"
+    "test_add_persistent_index"
+    "test_add_ttl_index"
+    "test_delete_index"
+    "test_pregel_management"
+
+    # formatting error - try enabling later
+    # maybe missed 3.9.3->3.10.0 changes
+    # caused by: body["computedValues"] = None
+    "test_permission_management"
+    "test_collection_misc_methods"
+    "test_collection_management"
+    "test_replication_inventory"
+
+    # want outgoing network to update foxx apis
+    # so foxx.api disabled in arangod startup
+    "test_foxx_service_management_file"
+    "test_foxx_service_management_json"
+    "test_foxx_config_management"
+    "test_foxx_dependency_management"
+    "test_foxx_development_toggle"
+    "test_foxx_misc_functions"
+
+    # no replication configured via arangod invocation
+    "test_replication_applier"
+  ];
+
+  pythonImportsCheck = [ "arango" ];
+
+  meta = with lib; {
+    description = "Python Driver for ArangoDB";
+    homepage = "https://github.com/ArangoDB-Community/python-arango";
+    license = licenses.mit;
+    maintainers = [ maintainers.jsoo1 ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 2c8945f53617..c16e227ddb7f 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8979,6 +8979,8 @@ self: super: with self; {
 
   python3-openid = callPackage ../development/python-modules/python3-openid { };
 
+  python-arango = callPackage ../development/python-modules/python-arango { };
+
   python-awair = callPackage ../development/python-modules/python-awair { };
 
   python3-saml = callPackage ../development/python-modules/python3-saml { };