diff --git a/maintainers/team-list.nix b/maintainers/team-list.nix
index 66cba166f2ca..8076edacd81a 100644
--- a/maintainers/team-list.nix
+++ b/maintainers/team-list.nix
@@ -70,6 +70,14 @@ with lib.maintainers; {
     scope = "Maintain the Chia blockchain and its dependencies";
   };
 
+  cosmopolitan = {
+    members = [
+      lourkeur
+      tomberek
+    ];
+    scope = "Maintain the Cosmopolitan LibC and related programs.";
+  };
+
   deshaw = {
     # Verify additions to this team with at least one already existing member of the team.
     members = [
diff --git a/nixos/doc/manual/from_md/release-notes/rl-2205.section.xml b/nixos/doc/manual/from_md/release-notes/rl-2205.section.xml
index 0c5b3b4fec76..66bc74310c9e 100644
--- a/nixos/doc/manual/from_md/release-notes/rl-2205.section.xml
+++ b/nixos/doc/manual/from_md/release-notes/rl-2205.section.xml
@@ -1253,6 +1253,13 @@
           example.
         </para>
       </listitem>
+      <listitem>
+        <para>
+          <literal>pkgs.cosmopolitan</literal> no longer provides the
+          <literal>cosmoc</literal> command. It has been moved to
+          <literal>pkgs.cosmoc</literal>.
+        </para>
+      </listitem>
     </itemizedlist>
   </section>
   <section xml:id="sec-release-22.05-notable-changes">
diff --git a/nixos/doc/manual/release-notes/rl-2205.section.md b/nixos/doc/manual/release-notes/rl-2205.section.md
index 7cafdcabbaaf..64fa68ddc620 100644
--- a/nixos/doc/manual/release-notes/rl-2205.section.md
+++ b/nixos/doc/manual/release-notes/rl-2205.section.md
@@ -444,6 +444,8 @@ In addition to numerous new and upgraded packages, this release has the followin
 
   See the `vscode` package for a more detailed example.
 
+- `pkgs.cosmopolitan` no longer provides the `cosmoc` command. It has been moved to `pkgs.cosmoc`.
+
 <!-- To avoid merge conflicts, consider adding your item at an arbitrary place in the list instead. -->
 
 ## Other Notable Changes {#sec-release-22.05-notable-changes}
diff --git a/pkgs/development/interpreters/python-cosmopolitan/default.nix b/pkgs/development/interpreters/python-cosmopolitan/default.nix
new file mode 100644
index 000000000000..14459a24aac2
--- /dev/null
+++ b/pkgs/development/interpreters/python-cosmopolitan/default.nix
@@ -0,0 +1,39 @@
+{ lib, stdenv, cosmopolitan, unzip, bintools-unwrapped }:
+
+stdenv.mkDerivation rec {
+  pname = "python-cosmopolitan";
+  version = "3.6.14";
+
+  src = cosmopolitan.dist;
+
+  patches = [
+    ./ioctl.patch        # required /dev/tty
+  ];
+
+  nativeBuildInputs = [ bintools-unwrapped unzip ];
+
+  # slashes are significant because upstream uses o/$(MODE)/foo.o
+  buildFlags = "o//third_party/python";
+  checkTarget = "o//third_party/python/test";
+  enableParallelBuilding = true;
+
+  doCheck = true;
+  dontConfigure = true;
+  dontFixup = true;
+
+  installPhase = ''
+    runHook preInstall
+    install o/third_party/python/*.com -Dt $out/bin
+    runHook postInstall
+  '';
+
+  meta = with lib; {
+    homepage = "https://justine.lol/cosmopolitan/";
+    description = "Actually Portable Python using Cosmopolitan";
+    platforms = platforms.x86_64;
+    badPlatforms = platforms.darwin;
+    license = licenses.isc;
+    maintainers = teams.cosmopolitan.members;
+    mainProgram = "python.com";
+  };
+}
diff --git a/pkgs/development/libraries/cosmopolitan/ioctl.patch b/pkgs/development/interpreters/python-cosmopolitan/ioctl.patch
similarity index 100%
rename from pkgs/development/libraries/cosmopolitan/ioctl.patch
rename to pkgs/development/interpreters/python-cosmopolitan/ioctl.patch
diff --git a/pkgs/development/libraries/cosmopolitan/default.nix b/pkgs/development/libraries/cosmopolitan/default.nix
index ca303fdeaea3..f58e654cbfe3 100644
--- a/pkgs/development/libraries/cosmopolitan/default.nix
+++ b/pkgs/development/libraries/cosmopolitan/default.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, fetchFromGitHub, runCommand, unzip, cosmopolitan,bintools-unwrapped }:
+{ lib, stdenv, fetchFromGitHub, unzip, bintools-unwrapped }:
 
 stdenv.mkDerivation rec {
   pname = "cosmopolitan";
@@ -11,72 +11,35 @@ stdenv.mkDerivation rec {
     sha256 = "sha256-UjL4wR5HhuXiQXg6Orcx2fKiVGRPMJk15P779BP1fRA=";
   };
 
-  patches = [
-    ./ioctl.patch        # required /dev/tty
-  ];
+  nativeBuildInputs = [ bintools-unwrapped unzip ];
 
-  postPatch = ''
-    patchShebangs build/
-  '';
+  outputs = [ "out" "dist" ];
 
+  # slashes are significant because upstream uses o/$(MODE)/foo.o
+  buildFlags = "o/cosmopolitan.h o//cosmopolitan.a o//libc/crt/crt.o o//ape/ape.o o//ape/ape.lds";
+  checkTarget = "o//test";
+  enableParallelBuilding = true;
+
+  doCheck = true;
   dontConfigure = true;
   dontFixup = true;
-  enableParallelBuilding = true;
-  nativeBuildInputs = [ bintools-unwrapped unzip ];
 
   installPhase = ''
     runHook preInstall
-    mkdir -p $out/{bin,include,lib}
+    mkdir -p $out/{include,lib}
     install o/cosmopolitan.h $out/include
     install o/cosmopolitan.a o/libc/crt/crt.o o/ape/ape.{o,lds} $out/lib
 
-    cat > $out/bin/cosmoc <<EOF
-    #!${stdenv.shell}
-    exec ${stdenv.cc}/bin/${stdenv.cc.targetPrefix}gcc \
-      -O -static -nostdlib -nostdinc -fno-pie -no-pie -mno-red-zone \
-      "\$@" \
-      -Wl,--gc-sections -Wl,-z,max-page-size=0x1000 \
-      -fuse-ld=bfd -Wl,-T,$out/lib/ape.lds \
-      -include $out/include/cosmopolitan.h \
-      -I $out/include \
-      $out/lib/{crt.o,ape.o,cosmopolitan.a}
-    EOF
-    chmod +x $out/bin/cosmoc
-
-    pushd o
-    find -iname "*.com" -type f -exec install -D {} $out/{} \;
-    popd
-    find -iname "*.h" -type f -exec install -m644 -D {} $out/include/{} \;
-    find -iname "*.inc" -type f -exec install -m644 -D {} $out/include/{} \;
+    cp -RT . "$dist"
     runHook postInstall
   '';
 
-  passthru.tests = lib.optionalAttrs (stdenv.buildPlatform == stdenv.hostPlatform) {
-    hello = runCommand "hello-world" { } ''
-      printf '#include "libc/stdio/stdio.h"\nmain() { printf("hello world\\n"); }\n' >hello.c
-      ${stdenv.cc}/bin/gcc -g -O -static -nostdlib -nostdinc -fno-pie -no-pie -mno-red-zone -o hello.com.dbg hello.c \
-        -fuse-ld=bfd -Wl,-T,${cosmopolitan}/lib/ape.lds \
-        -include ${cosmopolitan}/include/cosmopolitan.h \
-        -I ${cosmopolitan}/include \
-        ${cosmopolitan}/lib/{crt.o,ape.o,cosmopolitan.a}
-      ${stdenv.cc.bintools.bintools_bin}/bin/objcopy -S -O binary hello.com.dbg hello.com
-      ./hello.com
-      printf "test successful" > $out
-    '';
-    cosmoc = runCommand "cosmoc-hello" { } ''
-      printf '#include "libc/stdio/stdio.h"\nmain() { printf("hello world\\n"); }\n' >hello.c
-      ${cosmopolitan}/bin/cosmoc hello.c
-      ./a.out
-      printf "test successful" > $out
-    '';
-  };
-
   meta = with lib; {
     homepage = "https://justine.lol/cosmopolitan/";
     description = "Your build-once run-anywhere c library";
     platforms = platforms.x86_64;
     badPlatforms = platforms.darwin;
     license = licenses.isc;
-    maintainers = with maintainers; [ lourkeur tomberek ];
+    maintainers = teams.cosmopolitan.members;
   };
 }
diff --git a/pkgs/development/tools/cosmoc/default.nix b/pkgs/development/tools/cosmoc/default.nix
new file mode 100644
index 000000000000..f1e80d91df55
--- /dev/null
+++ b/pkgs/development/tools/cosmoc/default.nix
@@ -0,0 +1,40 @@
+{ stdenv, lib, cosmopolitan }:
+
+stdenv.mkDerivation {
+  pname = "cosmoc";
+  inherit (cosmopolitan) version;
+
+  doInstallCheck = true;
+  dontUnpack = true;
+  dontBuild = true;
+
+  installPhase = ''
+    runHook preInstall
+    mkdir -p $out/bin
+    cat <<EOF >$out/bin/cosmoc
+    #!${stdenv.shell}
+    exec ${stdenv.cc}/bin/${stdenv.cc.targetPrefix}gcc \
+      -O -static -nostdlib -nostdinc -fno-pie -no-pie -mno-red-zone \
+      "\$@" \
+      -Wl,--gc-sections -Wl,-z,max-page-size=0x1000 \
+      -fuse-ld=bfd -Wl,-T,${cosmopolitan}/lib/ape.lds \
+      -include ${cosmopolitan}/include/cosmopolitan.h \
+      ${cosmopolitan}/lib/{crt.o,ape.o,cosmopolitan.a}
+    EOF
+    chmod +x $out/bin/cosmoc
+    runHook postInstall
+  '';
+
+  installCheckPhase = ''
+    printf 'main() { printf("hello world\\n"); }\n' >hello.c
+    $out/bin/cosmoc hello.c
+    ./a.out
+  '';
+
+  meta = with lib; {
+    homepage = "https://justine.lol/cosmopolitan/";
+    description = "compiler for Cosmopolitan C programs";
+    license = licenses.mit;
+    maintainers = teams.cosmopolitan.members;
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 59cd11132018..3dd27785c49e 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -16534,8 +16534,12 @@ with pkgs;
 
   cog = callPackage ../development/web/cog { };
 
+  cosmoc = callPackage ../development/tools/cosmoc { };
+
   cosmopolitan = callPackage ../development/libraries/cosmopolitan { };
 
+  python-cosmopolitan = callPackage ../development/interpreters/python-cosmopolitan { };
+
   ctl = callPackage ../development/libraries/ctl { };
 
   ctpp2 = callPackage ../development/libraries/ctpp2 { };